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mazen hamed cv

Mazen Hamed
1306 Ft. Stockton Dr.
San Diego
92103
Phone:
Cell: ------------
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EXECUTIVE SUMMARY
Looking for an opportunity to expand Research on DNA binding proteins both experimentally and theoretically using MD simulations. Drug design (Kinase inhibitors) employing MD derived energies.
EMPLOYMENT HISTORY
Research Associate
Chemistry, Physical chemistry division, UC, San Diego 
July 2008 — July, 2009 (1 year)
Fulbright award, visiting Scholar UC, San Diego
-Theoretical research on DNA binding proteins and energy calculations
Research Associte
UC Berkeley 
July 1989 — July 1990 (1 year)
Fulbright award, visiting Scholar UC, Berkeley.
-Experimental Research on protein preparation and DNA binding of proteins.
Assistant professor & Associate professor of Chemistry
Birzeit University 
January 1983 — August 2018 (35 years 7 months)
Associate professor 1992 Research: DNA binding proteins like ferric uptake regulation protein, zinc finger protein
Understanding specificity and binding modes Kinase inhibitors as potential drugs-MD simulations Experimental instrumentation used electronic, ir, nmr, epr, GC-MS, gel electrophoresis, atomic absorption
Magnetic studies, Theory: Unix based Amber MD package -Thesis supervision of chemistry and computational science graduate students -Administrative positions: -department chair assistant -vice-president for academic affairs -Teaching graduate and undergraduate Inorganic Chemistry courses and Molecular modeling courses
Teaching Experience: Freshman Chemistry (Theory and Labs), Inorganic Chemistry (senior courses both theory and experiments), Graduate courses Molecular Modeling, Water quality and environmental chemistry, bio-inorganic, Inorganic)
Thesis supervision in computational chemistry
EDUCATION
Essex University, United Kingdom
PhD Chemistry, PhD Chemistry
June, 1981 — August, 1983
Degree date: 1983
University of Jordan
Bachelor of Chemistry, Chemistry
August, 1974 — August, 1978
Degree date: 1978
ACHIEVEMENTS
British council awards 1979, 1980 for PhD study, for research 1984, 1985, Fulbright award, visiting Scholar UC, Berkeley USA1989
Fulbright award, visiting scholar UC, San Diego USA 2008
Associate of the International center for theoretical physics TWAS grants 1992, 1994
Several research grants from Birzeit University 2000, 2003, 2014, 2017
-Publications:
Zinc Finger Protein-DNA Recognition Patterns: The Effect of Finger Linkers on DNA Binding
Mazen Y Hamed* & Roza Zaid and Rima M. Siam: submitted to Journal of computational biology and chemistry 2017
Hamed M. Y. (2018) Role of protein structure and the role of individual fingers in zinc finger protein–DNA recognition: a molecular dynamics simulation study and free energy calculations Journal of Computer-Aided Molecular Design, Incorporating Perspectives in Drug Discovery and Design, J Comput Aided Mol Des.
DOI 10.1007/s-------------9.
Hamed, M. Y., & Arya, G. (2016). Zinc Finger Protein Binding to DNA: An Energy Perspective Using Molecular Dynamics Simulation and Free Energy Calculations on Mutants of both Zinc Finger Domains and their Specific DNA bases. Journal of Biomolecular Structure and Dynamics, 34(5), 919–934.
Hamed, M.Yand Jabour, S. : Iron(II) Triggered Conformational Changes in E.coli Fur upon DNA binding: A study using Molecular dynamics, J. Mol. Graphics and Modeling 25, 234-246(2006)
Hamed, M.Y. and Jabour, S. Binding of the Zn2+ ion to ferric uptake regulation protein from E. coli and the competition with Fe2+ binding: a molecular modeling study of the effect on DNA binding and conformational changes of Fur, J Comput. Aided Mol Des (2009) 23:199–208
Hamed M.Y. and Neilands,J.B. : An electron spin resonance study of the Mn(II) and Cu(II) complexes of the Fur repressor protein, J. Inorg .Biochem, 53,235-248 (1993).
Hamed M.Y. and Neilands J.B. Binding of the ferric uptake regulation repressor protein(Fur) to Cu(II), Mn(II), Fe(II) and Co(II) ions as co-repressors. Electronic absorption, equilibrium and Fe Mossbauer study.,J.Inorg.Biochem,50,193- 220,(1993).
Hamed M.Y. Wilson,M.T., Silver,J. Keypour,H.: Studies on the Reactions of Iron(II) Ascorbate mixtures with molecular oxygen in solution,Inorg.Chim.Acta,152,227-231 (19884-7.Hamed,M.Y.,Wilson,M.T.,Silver,J.and Keypour,H.: Studies on the reactions of ferric iron with ascorbic acid. A study of the solution chemistry using Mossbauer spectroscopy and stopped flow techniques, Inorg.Chim.Acta, 125,97-106(1986)Hamed, M.Y, Jensen,P., Wilson, M.T. and Silver J.: Electron Spin Resonance study of rapidly frozen solution of iron glutathione,Inog.Chim.Acta,125,1-4(1986).
Hamed,M.Y.,Silver,J.Morrison,I.(In part): Studies On the reactions of ferric iron with glutathione and some related thiols, part(v). Solid complexes containing Fe(II) and GSH and Fe(III) and GSSG,Inorg.Chim.Acta,107,169-178(1985).
Hamed,M.Y.,Silver,J.,and Wilson,M.T.: A study of iron catalyzed oxidation of glutathione by molecular oxygen, Inorg.Chim.Acta,80,237-244(1983).
Hamed,M.Y.and Silver,J.: Studies on the reaction of Ferric iron with