David Aiyedun
David Aiyedun
Technical skills
? Professional knowledge of aseptic processes with techniques, cGMP, GLP and good documentation practices. Operational knowledge of process automation systems such as SCADA DCS, Foxboro DCS, Lab Ware & Thermo LIMS, SAP ECC, Unicorn software with AKTA, Waters ACQUITY UPLC, Waters Xevo G2-XS QTof and Waters UNIFI software. Competency with Microsoft Office applications.
? Analytical techniques inclusive of Bioburden testing, Bradford Assay, Density Meter analysis, UV-Vis Spectrophotometry, SDS-PAGE and Endoproteinase digests, Intact Mass Analysis, Peptide Mapping and Released Glycan Analysis.
Experience
AbbVie Inc. February 2017 � December 2018
Manufacturing technician (Downstream Processing)
? Compliantly performed unit protein purification operations using Affinity Chromatography, SP Cation Exchange Chromatography, Ceramic Hydroxyapatite Chromatography, Viral Filtration, UF/DF, and Aseptic Fill to produce Therapeutic Monoclonal Antibodies; Vedolizumab (Entyvio).
? Meticulously executed unit protein purification operations with the use of Poros HQ Anion Exchange Chromatography, UF/DF, Viral Inactivation and Aseptic Finish to produce Therapeutic Fusion proteins; Recombinant Coagulation Factor IX with Albumin (Idelvion).
? Ensured the implementation of Batch records and SOPs for CIPs, SIPs, Filter Integrity tests, pH and Conductivity tests, UV-Vis Spectrophotometry, Density Meter Analysis and Chromatography Column packing operations.
Pfizer Pharmaceuticals October 2015 � Nov 2016
Associate scientist (Microbiology)
? Environmental and Personnel monitoring procedures to support Manufacturing and Cell Banking Suite using SCADA DCS, LabWare LIMS and Equipment (Lasair III & MAS-100).
? Routine in process testing for Bioburden samples (Membrane Filtration method).
Amgen Biopharmaceuticals September 2014 � June 2015
Senior manufacturing associate (Drug Substance and Drug Product)
? Performed designated steps: (Fractogel & Sephacryl Resin packing and sanitization) for Ion Exchange and Size Exclusion Chromatography using BPG column, AKTA skid and Unicorn software.
? Routinely sterilized equipment and formulated buffers to support manufacturing processes and prepared sterilized components to support upstream and downstream processes.
Sanofi-Genzyme July 2013 � September 2014
Manufacturing technician (Upstream Processing and Equipment Preparation)
? Performed monitoring of bioreactor fed-batch cell cultivation, with parameters to control and manage temperature, pH, mechanical agitation and aerobic/anaerobic bioprocessing.
? Worked with the autoclave, parts washer, filter integrity tester, pH & conductivity testing units to prepare equipment and parts. Performed preventative maintenance of processing equipment.
Education
Certifications and Trainings:
Northeastern University College of Science, Boston MA
Graduate Certificate in Biopharmaceutical Analytical Sciences (anticipated completion December, 2019)
Protein Mass Spectrometry and Glycoprotein Drug Analysis:
? Sample preparation
? In-gel digest and In-solution digest.
? SDS-PAGE.
? Mass spectrometry analysis
? Intact Protein Analysis and Top-Down Protein Sequencing.
? Peptide Mass Fingerprinting and Sequencing.
? Post Translational Modifications.
? Released Glycan Analysis.
? Data analysis
? Database searches of MS and MS-MS data and spectral libraries.
? Experiential Network Project: Biomarker identification for Alzheimer�s disease In Women�s Health.
University Of Ado-Ekiti UNAD
Bachelor of Science in Microbiology
Laboratory techniques and relevant courses:
? Bacterial identification, culture, enumeration and aseptic techniques.
? Mycology, Industrial Microbiology and Quality Control.
Mount Wachusett Community College
Advanced Manufacturing (Quality Systems Training Course)
Biopharmaceutical Analysis Training Lab (Northeastern University College of Science)
Intact Protein Analysis (Biopharmaceutical Analysis Training Course)
Quinsigamond Community College
Certificate in Biotechnology
David Aiyedun
Technical skills
? Professional knowledge of aseptic processes with techniques, cGMP, GLP and good documentation practices. Operational knowledge of process automation systems such as SCADA DCS, Foxboro DCS, Lab Ware & Thermo LIMS, SAP ECC, Unicorn software with AKTA, Waters ACQUITY UPLC, Waters Xevo G2-XS QTof and Waters UNIFI software. Competency with Microsoft Office applications.
? Analytical techniques inclusive of Bioburden testing, Bradford Assay, Density Meter analysis, UV-Vis Spectrophotometry, SDS-PAGE and Endoproteinase digests, Intact Mass Analysis, Peptide Mapping and Released Glycan Analysis.
Experience
AbbVie Inc. February 2017 � December 2018
Manufacturing technician (Downstream Processing)
? Compliantly performed unit protein purification operations using Affinity Chromatography, SP Cation Exchange Chromatography, Ceramic Hydroxyapatite Chromatography, Viral Filtration, UF/DF, and Aseptic Fill to produce Therapeutic Monoclonal Antibodies; Vedolizumab (Entyvio).
? Meticulously executed unit protein purification operations with the use of Poros HQ Anion Exchange Chromatography, UF/DF, Viral Inactivation and Aseptic Finish to produce Therapeutic Fusion proteins; Recombinant Coagulation Factor IX with Albumin (Idelvion).
? Ensured the implementation of Batch records and SOPs for CIPs, SIPs, Filter Integrity tests, pH and Conductivity tests, UV-Vis Spectrophotometry, Density Meter Analysis and Chromatography Column packing operations.
Pfizer Pharmaceuticals October 2015 � Nov 2016
Associate scientist (Microbiology)
? Environmental and Personnel monitoring procedures to support Manufacturing and Cell Banking Suite using SCADA DCS, LabWare LIMS and Equipment (Lasair III & MAS-100).
? Routine in process testing for Bioburden samples (Membrane Filtration method).
Amgen Biopharmaceuticals September 2014 � June 2015
Senior manufacturing associate (Drug Substance and Drug Product)
? Performed designated steps: (Fractogel & Sephacryl Resin packing and sanitization) for Ion Exchange and Size Exclusion Chromatography using BPG column, AKTA skid and Unicorn software.
? Routinely sterilized equipment and formulated buffers to support manufacturing processes and prepared sterilized components to support upstream and downstream processes.
Sanofi-Genzyme July 2013 � September 2014
Manufacturing technician (Upstream Processing and Equipment Preparation)
? Performed monitoring of bioreactor fed-batch cell cultivation, with parameters to control and manage temperature, pH, mechanical agitation and aerobic/anaerobic bioprocessing.
? Worked with the autoclave, parts washer, filter integrity tester, pH & conductivity testing units to prepare equipment and parts. Performed preventative maintenance of processing equipment.
Education
Certifications and Trainings:
Northeastern University College of Science, Boston MA
Graduate Certificate in Biopharmaceutical Analytical Sciences (anticipated completion December, 2019)
Protein Mass Spectrometry and Glycoprotein Drug Analysis:
? Sample preparation
? In-gel digest and In-solution digest.
? SDS-PAGE.
? Mass spectrometry analysis
? Intact Protein Analysis and Top-Down Protein Sequencing.
? Peptide Mass Fingerprinting and Sequencing.
? Post Translational Modifications.
? Released Glycan Analysis.
? Data analysis
? Database searches of MS and MS-MS data and spectral libraries.
? Experiential Network Project: Biomarker identification for Alzheimer�s disease In Women�s Health.
University Of Ado-Ekiti UNAD
Bachelor of Science in Microbiology
Laboratory techniques and relevant courses:
? Bacterial identification, culture, enumeration and aseptic techniques.
? Mycology, Industrial Microbiology and Quality Control.
Mount Wachusett Community College
Advanced Manufacturing (Quality Systems Training Course)
Biopharmaceutical Analysis Training Lab (Northeastern University College of Science)
Intact Protein Analysis (Biopharmaceutical Analysis Training Course)
Quinsigamond Community College
Certificate in Biotechnology